Deploying Digital Twins and Synthetic Data in Evidence Generation - The Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard
Webinar
March 19, 2026 @ 1:00 pm – 2:00 pm
This webinar will examine the use of digital twins and synthetic data in evidence generation, focusing on (1) their emerging applications across the clinical trial lifecycle, including study design, control arm reduction, and single-arm trials, and (2) regulatory expectations and experience. Panelists will discuss how evidence quality, validation approaches, performance benchmarks, and model interpretability shape decision-making, and reflect on how practical and regulatory considerations influence the adoption of these approaches in clinical research. The discussion will draw on use cases, including synthetic controls and power enhancement strategies, and will include a moderated discussion and time for audience Q&A.
Panelists:
- Daniele Bertolini, Principal Scientist, Unlearn.AI
- Tala Fakhouri, Vice President: Consulting, AI & Digital Policy, Real-World Research, Parexel
- Karen Smith, Board of Directors at Context Therapeutics, Skye Bioscience, and Sangamo Therapeutics; Principal and Co-Founder of Boomerang Biopathways.
Moderator: Barbara Bierer, Faculty Director, MRCT Center