Childhood Cancer Academic-Industry Collaborative Platform Trials (C3PT): Toolkit Launch Webinar - The Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard

The MRCT Center, in collaboration with ITCC (Innovative Therapies for Children and Adolescents with Cancer), Blood Cancer United, and the Children’s Oncology Group, will launch the Childhood Cancer Academic-Industry Collaborative Platform Trials (C3PT) Position Narrative and Toolkit, guidance for those planning and delivering platform trials for pediatric oncology.

The toolkit release marks the culmination of a two-year multi-stakeholder effort. In October 2024, the MRCT Center convened a group of experts for a two-day workshop, “Advancing Pediatric Platform Trials: Streamlining Development, Maximizing Impact,” that examined platform trials across pediatric oncology, major depressive disorder, and multidrug-resistant tuberculosis. A July 2025 follow-on workshop focused specifically on pediatric oncology, developing an implementation framework for academic and industry platform studies.

The C3PT resource includes a range of tools that support the user in putting that framework into practice. The toolkit offerings guide the user in determining whether a platform trial is the right trial design, what the optimal timing is for sponsor and regulatory interactions, guidance on templated sections for PIPs and iPSPs, considerations related to intellectual property and contracting, operational planning, and funding models.

The webinar will include opening remarks, a moderated multi-stakeholder discussion, and audience Q&A.

Deliverables