Clinical Research Glossary

Pharmacodynamic (PD) study Pharmacodynamic (PD) study


A study that measures the effects of a drug on the human body.

Example of Pharmacodynamic (PD) study in a sentence

During a pharmacodynamic study a participant will have their blood and other body fluids collected a few times over a few hours to see how the dose of the study treatment affects their body.

More Info

A pharmacodynamic (PD) study is the study of the effects of the drug on the human body. A PD study helps researchers learn whether the study treatment is having the desired effect on the body, and how the dose of the drug affects the response. For example, a PD study could try to find out if a drug for cancer will attach to a cancer cell and lead to the cell’s death.

Other info to think about when joining a study

You might see the term “pharmacodynamic study”, when researchers want to find out what effect the drug has on participants‘ bodies and how their bodies react. This is different from a pharmacokinetic study where the effect of the body on the drug is measured. Researchers use this information to design clinical trials, for example, what doses to give to participants. Because of this, pharmacodynamic studies are usually conducted early in the research process to help guide what is the best dosage for humans to take and to also look at safety in general.

If you are considering participating in a pharmacodynamic study you can ask the researchers about what is already known about the drug, and how the study team will be monitoring the safety of the participants.

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