n-of-1 study n-of-1 study
A research study testing one or more study treatments in a single participant to find the best treatment for that person.
Example of n-of-1 study in a sentence
In an n-of-1 study, a participant may try several different study treatments to see which one works best for them.
More Info
N-of-1 studies may be conducted in rare diseases or conditions where there are fewer patients or individual responses may be unique. N-of-1 studies may also be. conducted in chronic diseases or conditions. This type of study design tries to see which study treatment is best for the individual participant, while still collecting data to support general learning.
N-of-1 studies can still be randomized and blinded.
N-of-1 studies can also be used to collect information about health technologies and devices, not just study treatments.
In n-of-1 studies, data from multiple individuals could also be combined to support more general conclusions. There may be analyses of the data collected from the individuals to see if they can be applied more broadly to the population level.
Other info to think about when joining a study
An “n-of-1 study” is a type of personalized medicine that collects data during the process of trying out different treatments
If you are thinking about joining an n-of-1 study, you may ask the study team about the study treatments that will be used and what order they will be given. You can also ask how being part of the study could affect your overall healthcare and treatment for your condition, like if you will be able to keep using the treatment that worked best for you.
