Clinical Research Glossary

dose escalation study dose escalation study

CDISC

A kind of study where increasing amounts of a study treatment are given to different groups to find the best dose.

Example of dose escalation study in a sentence

In a dose-escalation study, the dose of a study treatment is increased one group at a time to find the best dose.

More Info

In a dose-escalation study, the first participant (or group of participants) gets the lowest dose of study medication.

The amount is increased with each participant or group to find the dose that gives the greatest benefit with the fewest side effects.

This process can help researchers choose the best dose for future studies.

Other info to think about when joining a study

If you are considering participating in a dose escalation study, you may have questions about how the dose levels were determined and what safety information already exists.

Feel free to ask the study team any questions you might have.

Version 2.0 September 2024

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