QUALITY AND TRANSPARENCY
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Use of AI as a Research Recruitment Tool: Ethical Elements, Considerations, and Recommendations

Publication

Published on: April 10, 2026

Published in: American Journal of Bioethics

Description: Barbara Bierer and Trevor Baker of the MRCT Center, with Donna Snyder of WCG and Peter Rentzepis, formerly of Harvard Medical School, published “Use of AI as a Research Recruitment Tool: Ethical Elements, Considerations, and Recommendations” in the American Journal of Bioethics. Recruitment is often the most time-consuming and costly stage of a clinical trial, making it a frequent target for AI implementation, yet formal regulatory guidance and best practices for AI-driven recruitment remain limited. The authors examine AI use across five domains of the recruitment process and advance a framework of ethical considerations and recommendations to inform investigators, sponsors, CROs, regulators, and IRBs as they develop, test, and evaluate these tools.



Rentzepis, P., Snyder, D. L., Baker, T., & Bierer, B. E. (2026). Use of AI as a Research Recruitment Tool: Ethical Elements, Considerations, and Recommendations. The American Journal of Bioethics, 1–21. https://doi.org/10.1080/15265161.2026.2649234